#FIB-RW-23000676Reading & Writing: Fill in the BlanksCore & AcademicHard

Blood Pressure Remedy

Official Question Material
Prep: Varies

Here's a possible blood [blank] remedy. But it's only for those who can stand the heat. It's capsaicin, the "active ingredient" in peppers like habaneros that should probably be sold by prescription only. While lips burn and eyes water, blood vessels actually relax, thanks to [blank] production of the signaling molecule nitric oxide. In rodents, anyway. For seven months, researchers in China fed a steady diet of capsaicin to rats bred to be hypertensive. Long-term consumption of the chemical [blank] lowered the rats' blood pressure. The results appear in the August issue of the journal Cell Metabolism. Previous research found mixed results with capsaicin, but those studies only looked at short-term [blank] . Human trials are needed, but there's already a clue. Some 20 percent of people in northeastern China have high blood pressure. But in the southwest, where hot peppers are a dietary staple has a much [blank] incidence, half in some places. Human studies could also confirm whether the habanero, as legend has it, can cause hearing loss. Allegedly so that diners don't have to listen to their own screams.

Sample Answer & Audio Transcript

Here's a possible blood pressure remedy. But it's only for those who can stand the heat. It's capsaicin, the "active ingredient" in peppers like habaneros that should probably be sold by prescription only. While lips burn and eyes water, blood vessels actually relax, thanks to increased production of the signaling molecule nitric oxide. In rodents, anyway. For seven months, researchers in China fed a steady diet of capsaicin to rats bred to be hypertensive. Long-term consumption of the chemical substantially lowered the rats' blood pressure. The results appear in the August issue of the journal Cell Metabolism. Previous research found mixed results with capsaicin, but those studies only looked at short-term effects . Human trials are needed, but there's already a clue. Some 20 percent of people in northeastern China have high blood pressure. But in the southwest, where hot peppers are a dietary staple has a much lower incidence, half in some places. Human studies could also confirm whether the habanero, as legend has it, can cause hearing loss. Allegedly so that diners don't have to listen to their own screams.
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